Methylamine → HCID 58562170, compound

HRID 1406533Notes

Reaction equation

HRID 1406533 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([C:11]2[CH:31]=[CH:30][C:14]3[N:15]([CH3:29])[C:16]([NH:18][C:19]4[CH:27]=[CH:26][C:22]([C:23](O)=[O:24])=[CH:21][C:20]=4[Cl:28])=[N:17][C:13]=3[CH:12]=2)=[O:10])=[CH:4][CH:3]=1.CN.[CH3:34][N:35](C(ON1N=NC2C=CC=CC1=2)=[N+](C)C)C.[B-](F)(F)(F)F>C1COCC1>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9]([C:11]2[CH:31]=[CH:30][C:14]3[N:15]([CH3:29])[C:16]([NH:18][C:19]4[CH:27]=[CH:26][C:22]([C:23](=[O:24])[NH:35][CH3:34])=[CH:21][C:20]=4[Cl:28])=[N:17][C:13]=3[CH:12]=2)=[O:10])=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 6329MethylamineHCID 2733207O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborateHCID 67230253HCID 67230253, compound

Product 1

HCID 58562170HCID 58562170, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Prepared analogously to example 3c from 4-(5-(4-bromophenylcarbamoyl)-1-methyl-1H-benzimidazol-2-ylamino)-3-chlorobenzoic acid, methylamine (solution in THF), TBTU and TEA in THF.

Sources & evidence

ORD record
ord-2285d663b7ea49ee8e980a083f07d527
Source dataset
uspto-grants-2014_12
Patent number
US08916599B2

Reaction notes

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