1,1'-Thiocarbonyldi-2(1H)-pyridone → HCID 86646334, compound

HRID 1410190Notes

Reaction equation

HRID 1410190 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH:9]([NH:11][C:12](=[O:14])[CH3:13])[CH3:10])[CH:5]=[CH:6][C:7]=1[Cl:8].[C:15](N1C=CC=CC1=O)(N1C=CC=CC1=O)=[S:16]>CN(C1C=CN=CC=1)C.C(Cl)Cl>[Cl:8][C:7]1[CH:6]=[CH:5][C:4]([CH:9]([NH:11][C:12](=[O:14])[CH3:13])[CH3:10])=[CH:3][C:2]=1[N:1]=[C:15]=[S:16]

Participants

5

Reactant 2

HCID 8531621,1'-Thiocarbonyldi-2(1H)-pyridoneHCID 59529800HCID 59529800, compound

Product 1

HCID 86646334HCID 86646334, compound

Reagents, catalysts & solvents 2

HCID 142844-(Dimethylamino)pyridineCatalystHCID 6344DichloromethaneSolvent

Procedure

N-[1-(3-Amino-4-chlorophenyl)ethyl]acetamide (90 mg, 0.2 mmol) was added to a mixture of 1,1′-thiocarbonyldi-2-pyridone (69 mg, 0.2 mmol), DMAP (7 mg, 0.05 mmol) and DCM (2 mL) at rt. The mixture was concentrated and used in the next step without further purification.

Workup

  1. concentrationThe mixture was concentrated
  2. customused in the next step without further purification

Sources & evidence

ORD record
ord-3d8ff490b6f8494db2991573d585605c
Source dataset
uspto-grants-2014_12
Patent number
US08921405B2

Reaction notes

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