反应详情

温度

100 °C

A mixture of 4-amino-N-(4-bromophenyl)-2-methoxy-5-nitrobenzamide (1.30 g; 3.55 mmol), THF (80 mL) and EtOH (50 mL) was treated with AcOH (3 mL) and stirred for 15 min at 100° C. To the warm mixture, Fe (1.30 g; 23.3 mmol) was carefully added in portions and the resulting mixture was heated for 2 h at 100° C. The mixture was cooled, filtered through celite and concentrated to give the crude sub-title compound.

1. temperaturethe resulting mixture was heated for 2 h at 100° C
2. temperatureThe mixture was cooled
3. filtrationfiltered through celite and
4. concentrationconcentrated