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HRID1410263

反应详情

EQUATION

反应方程式

HRID 1410263 的结构方程式

REACTANTS

反应物

4
结构：COc1cc(N)c([N+](=O)[O-])cc1C(=O)O
HCID101016

4-Amino-2-methoxy-5-nitrobenzoic acid

C8H8N2O5

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：CCO.ClCCl
HCID21584144

Dichloromethane ethanol

C3H8Cl2O

结构：N[C@H]1CC[C@H](C(F)(F)F)CC1
HCID178511531

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(N)c([N+](=O)[O-])cc1C(=O)N[C@H]1CC[C@H](C(F)(F)F)CC1
HCID178493230

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

The sub-title compound was prepared from 2-methoxy-4-amino-5-nitro benzoic acid and trans-4-trifluoromethyl-cyclohexylamine with TBTU and TEA in DMF in analogy to example 3e._Yield: quantitative; TLC: silica gel, DCM/EtOH 9:1, Rf=0.68.