Hydrochloric Acid → HCID 59529857, compound

HRID 1410266Notes

Reaction equation

HRID 1410266 reaction equation

C(OC(=O)[NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]([F:18])([F:17])[F:16])=[C:11]([NH2:19])[CH:10]=1)(C)(C)C.Cl>C1COCC1>[NH2:19][C:11]1[CH:10]=[C:9]([CH:14]=[CH:13][C:12]=1[C:15]([F:16])([F:17])[F:18])[CH2:8][NH2:7]

Participants

4

Reactant 2

HCID 313Hydrochloric Acid

HCID 59529859HCID 59529859, compound

Product 1

HCID 59529857HCID 59529857, compoundYield 99%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

The title compound was prepared from tert.-butyl-N-(3-amino-4-trifluoromethyl-benzyl)carbamate and—6M HCl in THF in analogy to example 2e.

Sources & evidence

ORD record: ord-649af616d5884b75a133b328ae026f90
Source dataset: uspto-grants-2014_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08921405B2

Reaction notes

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