Hydrochloric Acid → HCID 57244169, compound

HRID 1413058Notes

Reaction equation

HRID 1413058 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[N:13][CH:14](Cl)[CH:15]([Cl:20])[C:16]([Cl:19])([Cl:18])[Cl:17])[C:11](=[O:22])[N:10]([CH3:23])[C:9]1=[O:24].[F:25][C:26]1[CH:32]=[CH:31][CH:30]=[CH:29][C:27]=1[NH2:28].C(N(CC)CC)C.Cl>C(#N)C.C(OCC)C>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[C:12](=[N:13][CH:14]([NH:28][C:27]2[CH:29]=[CH:30][CH:31]=[CH:32][C:26]=2[F:25])[CH:15]([Cl:20])[C:16]([Cl:19])([Cl:18])[Cl:17])[C:11](=[O:22])[N:10]([CH3:23])[C:9]1=[O:24]

Participants

7

Reactant 4

HCID 313Hydrochloric AcidHCID 8471TriethylamineHCID 95842-FluoroanilineHCID 57147756HCID 57147756, compound

Product 1

HCID 57244169HCID 57244169, compound

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6342AcetonitrileSolvent

Procedure

In this example 0.02 mol of 1-(2-fluorophenyl)-3-methyl-5-(1,2,3,3,3-pentachloropropyl)imino-1,3-diazolidine-2,4-dione is dissolved in 20 ml of acetonitrile and then 0.02 of mol of 2-fluoroaniline is added. After about 10 minutes, triethylamine is added to neutralize the byproduct HCl produced by the reaction. The mixture is stirred for five hours and 20 ml of ethyl ether is then added. The mixture is filtered and the filtrate evaporated under high vacuum affording 1-(2-fluorophenyl)-3-methyl-5-(1-2'-fluorophenylamino-2,3,3,3-tetrachloropropyl)imino-1,3-diazolidine-2,4-dione.

Workup

  1. customproduced by the reaction
  2. filtrationThe mixture is filtered
  3. customthe filtrate evaporated under high vacuum

Sources & evidence

ORD record
ord-db75ff93ad034b18bb515748aba4d08b
Source dataset
uspto-grants-1981_02
Patent number
US04248620

Reaction notes

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