反应详情

To a solution of the sulfonyl chloride in 10 ml tetrahydrofuran was added a solution of the hydrazinoquinoline and triethylamine in 30 ml tetrahydrofuran (4 ml dimethylformamide was included to aid solubility). The temperature of the reaction mixture was maintained below 10° C. during the addition and for 30 minutes thereafter while the mixture was continuously stirred. The product was recovered as in Example 1 yielding 8.4 g of a tan solid. NMR and IR analysis confirmed the product to be 2-(dodecylbenzenesulfonylhydrazino)quinoline.

1. temperatureThe temperature of the reaction mixture was maintained below 10° C. during the addition and for 30 minutes
2. customThe product was recovered as in Example 1 yielding 8.4 g of a tan solid