Lactic Acid → 2-(Dimethylamino)ethyl 2-hydroxypropanoate

HRID 1414153Notes

Reaction equation

HRID 1414153 reaction equation
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][OH:5].[C:7](O)(=[O:11])[CH:8]([CH3:10])[OH:9].C(O)(C)C>O>[C:7]([O:5][CH2:4][CH2:3][N:2]([CH3:6])[CH3:1])(=[O:11])[CH:8]([CH3:10])[OH:9]

Participants

5

Reactant 3

HCID 612Lactic AcidHCID 3776IsopropanolHCID 79022-(Dimethylamino)ethanol

Product 1

HCID 141792032-(Dimethylamino)ethyl 2-hydroxypropanoate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent3×

Procedure

The resin of this example was prepared in the presence of 5 percent water based on total solids, and had a water-to-amine nitrogen (of the amine acid salt) equivalency of 1.74:0.44. A dimethyl ethanolamine lactate was prepared by admixing 13.3 parts of dimethyl ethanolamine and 18.0 parts of lactic acid (85 percent solution in water). The mixture was held at 40°C. to 60°C. for a short time and there was then added 7.2 parts of isopropanol. The final composition consisted of 75 percent solids and contained 7.1 percent water.

Workup

  1. customwas held at 40°C. to 60°C. for a short time and there

Sources & evidence

ORD record
ord-db4ef79f13dd4ffdb27569ee3dae6cbc
Source dataset
uspto-grants-1977_01
Patent number
US04001156

Reaction notes

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