Potassium Carbonate → HCID 21487992, compound

HRID 1414611Notes

Reaction equation

HRID 1414611 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:19]=[C:18]([CH3:20])[CH:17]=[C:16]([CH3:21])[CH:15]=2)=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37]Cl)[CH3:34]>CC(C)=O>[CH2:33]([N:35]([CH2:39][CH3:40])[CH2:36][CH2:37][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]3[CH:26]=[CH:25][CH:24]=[CH:23][C:11]=3[C:12]=2[C:13](=[O:22])[C:14]2[CH:15]=[C:16]([CH3:21])[CH:17]=[C:18]([CH3:20])[CH:19]=2)=[CH:6][CH:7]=1)[CH3:34]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 13364Diethylaminoethyl chlorideHCID 21487920HCID 21487920, compound

Product 1

HCID 21487992HCID 21487992, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

2-p-Hydroxyphenyl-3-(3',5'-dimethylbenzoyl)benzofuran (5.25 g., 15.3 mmol.) was dissolved in 200 ml. of dry acetone and 10.5 g. (0.076 mol.) of potassium carbonate and 2.10 g. (15.3 mmol.) of 2-diethylaminoethyl chloride were added. The reaction mixture was refluxed for three hours, then it was cooled and filtered. The filtrate was concentrated at reduced pressure to give the title compound as an oil.

Workup

  1. temperatureThe reaction mixture was refluxed for three hours
  2. temperatureit was cooled
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated at reduced pressure

Sources & evidence

ORD record
ord-f3021689b5424ac09203357e407fc367
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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