Salicylaldehyde → HCID 21487944, compound

HRID 1414618Notes

Reaction equation

HRID 1414618 reaction equation
ClC1C=CC=C(O)C=1C=O.C(=O)C1C(=CC=CC=1)O.[Cl:20][C:21]1[C:26]2[CH:27]=[C:28]([C:30](=O)[C:31]3[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=3)[O:29][C:25]=2[CH:24]=[CH:23][CH:22]=1.O.NN>>[Cl:20][C:21]1[C:26]2[CH:27]=[C:28]([CH2:30][C:31]3[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=3)[O:29][C:25]=2[CH:24]=[CH:23][CH:22]=1

Participants

5

Reactant 4

HCID 6998SalicylaldehydeHCID 24654Hydrazine hydrate (1:1)HCID 5283932-Chloro-6-hydroxybenzaldehydeHCID 21487997HCID 21487997, compound

Product 1

HCID 21487944HCID 21487944, compound

Procedure

When an equivalent amount of 6-chlorosalicylaldehyde is used as a starting material in the procedure of Example 15 in place of salicylaldehyde and the product 4-chloro-2-(4'-methoxybenzoyl)benzofuran is reduced with hydrazine hydrate, 4-chloro-2-(4'-methoxybenzyl)benzofuran is obtained.

Sources & evidence

ORD record
ord-66f774a60c6b4ebfb2e1517bacf5c764
Source dataset
uspto-grants-1977_01
Patent number
US04001426

Reaction notes

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