Hydrochloric Acid → 4-[(2,2,3,3-Tetrafluoropropyl)sulfanyl]benzene-1,2-diamine

HRID 1414791Notes

Reaction equation

HRID 1414791 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([S:11][CH2:12][C:13]([F:18])([F:17])[CH:14]([F:16])[F:15])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-])=O.Cl.[OH-].[NH4+]>>[NH2:6][C:5]1[CH:7]=[CH:8][C:9]([S:11][CH2:12][C:13]([F:18])([F:17])[CH:14]([F:16])[F:15])=[CH:10][C:4]=1[NH2:1]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14923Ammonium HydroxideHCID 203711392-Nitro-4-[(2,2,3,3-tetrafluoropropyl)sulfanyl]aniline

Product 1

HCID 537273284-[(2,2,3,3-Tetrafluoropropyl)sulfanyl]benzene-1,2-diamine

Procedure

4 G. of 2-nitro-4-(2,2,3,3-tetrafluoropropylthio) aniline is treated with 24 g. of stannous chloride in 25 ml. on concentrated hydrochloric acid. The mixture is stirred for one-half hour, basified with ammonium hydroxide and extracted with chloroform. The chloroform solution is filtered, dried over sodium sulfate, and evaporated to give 1,2-diamino-4-(2,2,3,3-tetrafluoropropylthio) benzene.

Workup

  1. extractionextracted with chloroform
  2. filtrationThe chloroform solution is filtered
  3. dry with materialdried over sodium sulfate
  4. customevaporated

Sources & evidence

ORD record
ord-1df584d17a8d4c1f9d3e935feee18640
Source dataset
uspto-grants-1977_01
Patent number
US04002640

Reaction notes

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