Methylamine → 1-Nitro-2-methylamino-2-[4-(2-pyridyl)butylamino]ethylene

HRID 1414885Notes

Reaction equation

HRID 1414885 reaction equation
[N+:1]([CH:4]=[C:5](SC)[NH:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)([O-:3])=[O:2].[CH3:19][NH2:20]>>[N+:1]([CH:4]=[C:5]([NH:20][CH3:19])[NH:6][CH2:7][CH2:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 706192371-Nitro-2-methylthio-2-[4-(2-pyridyl)butylamino]ethylene

Product 1

HCID 706195171-Nitro-2-methylamino-2-[4-(2-pyridyl)butylamino]ethylene

Procedure

A mixture of 1-nitro-2-methylthio-2-[4-(2-pyridyl)-butylamino]ethylene and 33% ethanolic methylamine were heated on a steam bath for 15 minutes. Concentration, followed by crystallisation from ethyl acetate yielded the title compound m.p. 90°-91°. (Found: C, 57.8; H, 7.2; N, 22.6%. C12H18N4O2 requires: C, 57.6; H, 7.2; N, 22.4 %).

Workup

  1. temperaturewere heated on a steam bath for 15 minutes
  2. concentrationConcentration
  3. customfollowed by crystallisation from ethyl acetate

Sources & evidence

ORD record
ord-7c76eea86c1f46f99296299377c73bc8
Source dataset
uspto-grants-1977_01
Patent number
US04002759

Reaction notes

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