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HRID1414990

反应详情

EQUATION

反应方程式

HRID 1414990 的结构方程式

REACTANTS

反应物

4
结构：N
HCID222

Ammonia gas

H3N

结构：CCO
HCID702

Ethanol

C2H6O

结构：CC[C@]12CC[C@@H]3c4ccc(OC)cc4CC[C@H]3[C@@H]1CC[C@@H]2O
HCID66432

18-Methylestradiol-3-methyl ether

C20H28O2

结构：[Li]
HCID3028194

Lithium

Li

PRODUCTS

生成物

1
结构：CC[C@]12CC[C@@H]3C4=C(CC[C@H]3[C@@H]1CC[C@@H]2O)CC(OC)=CC4
HCID101950

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

3
结构：O
溶剂HCID962

Water

H2O

结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

Add 13β-Ethyl-3-methoxy-gona-1,3,5(10)-trien-17β-ol (0.5 g.) in tetrahydrofuran (50 cc.) to stirred liquid ammonia (150 cc.), followed by lithium foil (0.5 g.) and then add ethanol (6 cc.) during 20 minutes. When the blue color is discharged, add water and work up the product with ether, to yield 13β-ethyl-3-methoxy-gona-2,5(10)-dien-17β-ol as a solid (0.47 g.).