Phthalimide → HCID 21482311, compound

HRID 1415605Notes

Reaction equation

HRID 1415605 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=[O:30])[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]1[C:22]([CH2:23]O)=[C:21]([CH3:25])[N:20]=[C:19]1[CH2:26][N:27]([CH3:29])[CH3:28].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:50]1(=[O:60])[NH:54][C:53](=[O:55])[C:52]2=[CH:56][CH:57]=[CH:58][CH:59]=[C:51]12.N(C(OCC)=O)=NC(OCC)=O>>[N+:15]([C:13]1[CH:12]=[CH:11][C:10]([N:18]2[C:22]([CH2:23][N:54]3[C:50](=[O:60])[C:51]4=[CH:59][CH:58]=[CH:57][CH:56]=[C:52]4[C:53]3=[O:55])=[C:21]([CH3:25])[N:20]=[C:19]2[CH2:26][N:27]([CH3:29])[CH3:28])=[C:9]([C:8](=[O:30])[C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])[CH:14]=1)([O-:17])=[O:16]

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 21482343HCID 21482343, compound

Product 1

HCID 21482311HCID 21482311, compound

Procedure

In the manner given in Example 3, 2'-chloro-5-nitro-2-[2-[(dimethylamino)methyl]-4-methyl-5-hydroxymethylimidazol-1-yl]benzophenone, triphenylphosphine, phthalimide and thereafter diethyl azodicarboxylate are reacted together to give N-[[1-[4-nitro-2-(o-chlorobenzoyl)phenyl]-2-[(dimethylamino)methyl]-4-methylimidazol-5-yl]methyl]-phthalimide.

Sources & evidence

ORD record
ord-10211518f05b4c48919c9b4c90d496d2
Source dataset
uspto-grants-1977_01
Patent number
US04005099

Reaction notes

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