Phthalimide → HCID 21482307, compound

HRID 1415620Notes

Reaction equation

HRID 1415620 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH2:21]O)=[C:19]([CH3:23])[N:18]=[C:17]2[CH2:24][N:25]([CH3:27])[CH3:26])=[C:6]([CH:15]=1)[C:7]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)=[O:8].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:47]1(=[O:57])[NH:51][C:50](=[O:52])[C:49]2=[CH:53][CH:54]=[CH:55][CH:56]=[C:48]12.N(C(OCC)=O)=NC(OCC)=O>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([N:16]2[C:20]([CH2:21][N:51]3[C:47](=[O:57])[C:48]4=[CH:56][CH:55]=[CH:54][CH:53]=[C:49]4[C:50]3=[O:52])=[C:19]([CH3:23])[N:18]=[C:17]2[CH2:24][N:25]([CH3:27])[CH3:26])=[C:6]([C:7](=[O:8])[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)[CH:15]=1

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 21482288HCID 21482288, compound

Product 1

HCID 21482307HCID 21482307, compound

Procedure

In the manner given in Example 3, 5-chloro-2-[2-[(dimethylamino)methyl]-4-methyl-5-hydroxymethylimidazo1-yl]benzophenone, triphenylphosphine, phthalimide and thereafter diethyl azodicarboxylate are reacted together to give N-[[1-[4-chloro-2-(benzoyl)phenyl]-2-[(dimethylamino)methyl]-4-methylimidazol-5-yl]methyl]phthalimide.

Sources & evidence

ORD record
ord-d29d6ea12a944e7294435aac74d173ff
Source dataset
uspto-grants-1977_01
Patent number
US04005099

Reaction notes

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