Triphenylphosphine → 3-Cyano-4-nitrobenzyltriphenylphosphonium bromide

HRID 1416166노트

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[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([N+:10]([O-:12])=[O:11])=[C:6]([CH:9]=1)[C:7]#[N:8].C1C(=O)N([Br:20])C(=O)C1.[C:21]1([P:27]([C:34]2[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1>>[Br-:20].[C:7]([C:6]1[CH:9]=[C:2]([CH:3]=[CH:4][C:5]=1[N+:10]([O-:12])=[O:11])[CH2:1][P+:27]([C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1)([C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)#[N:8]

참가 물질

반응물 3

HCID 11776Triphenylphosphine

HCID 67184N-bromobutanimide

HCID 5607435-Methyl-2-nitrobenzonitrile

생성물 1

HCID 867541083-Cyano-4-nitrobenzyltriphenylphosphonium bromide

실험 절차

Benzylic bromination of 5-methyl-2-nitrobenzonitrile by NBS by the standard procedure followed by treatment of the resultant product (3b) with triphenylphosphine gave 3-cyano-4-nitrobenzyltriphenylphosphonium bromide in good yield.

출처 및 근거

ORD 기록: ord-c116b62fad6d42609f9b2ef1ba02902f
출처 데이터셋: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05912251

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