反应详情

1-(2-methylphenyl)-4-oxo-6-methyl-2,3,4,5-tetra hydropyrrolo[3,2-c]quinoline (290 mg, 1.0 mmol) was dissolved in 20 ml of diphenyl ether and 40 mg of 5% palladium/carbon was added. The reaction mixture was heated for 4 hours. The reaction mixture was cooled to the room temperature and directly purified by silica gel chromatography to obtain 245 mg of desired compound as solid in 85% of yield.

1. temperatureThe reaction mixture was heated for 4 hours
2. customdirectly purified by silica gel chromatography