Hydrochloric Acid → HCID 53714462, compound
Reaction equation
[CH2:1]([NH2:4])[CH:2]=[CH2:3].[F:5][C:6]([C:41]([F:44])([F:43])[F:42])([O:10][C:11]([F:40])([F:39])[C:12]([F:38])([C:34]([F:37])([F:36])[F:35])[O:13][C:14]([F:33])([F:32])[C:15]([F:31])([C:27]([F:30])([F:29])[F:28])[O:16][C:17]([F:26])([F:25])[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20])[C:7](F)=[O:8].Cl>>[CH2:1]([NH:4][C:7](=[O:8])[C:6]([F:5])([C:41]([F:42])([F:43])[F:44])[O:10][C:11]([F:39])([F:40])[C:12]([F:38])([C:34]([F:35])([F:36])[F:37])[O:13][C:14]([F:32])([F:33])[C:15]([F:31])([C:27]([F:30])([F:29])[F:28])[O:16][C:17]([F:26])([F:25])[C:18]([F:24])([F:23])[C:19]([F:22])([F:21])[F:20])[CH:2]=[CH2:3]Participants
4
Procedure
A 100 mL round bottom flask equipped with a magnetic stirring bar and an addition funnel was charged with 9.0 g of allyl amine (160 mmoles). The liquid was stirred and 40 g of 97% perfluoro-2,5,8-trimethyl-3,6,9-trioxadodecanoyl fluoride (60 mmoles) was added dropwise. Dilute hydrochloric acid was added to the flask and the two phase mixture was transferred into a separatory funnel and the aqueous layer separated from the amide layer. The amide layer was washed again with dilute hydrochloric acid and twice with water. The amide layer was transferred into a round bottom flask and distilled at 101° C. and 3 mmHg to yield a fraction of 21.6 (52% yield) of >99% N-allylperfluoro-2,5,8-trimethyl-3,6,9-trioxadodecanamide (31 mmoles).
Workup
- customA 100 mL round bottom flask equipped with a magnetic stirring bar and an addition funnel
- customthe two phase mixture was transferred into a separatory funnel
- customthe aqueous layer separated from the amide layer
- washThe amide layer was washed again with dilute hydrochloric acid and twice with water
- customThe amide layer was transferred into a round bottom flask
- distillationdistilled at 101° C.
Sources & evidence
- ORD record
- ord-b3ba711571b3429a82c15f293876614c
- Source dataset
- uspto-grants-1999_06
- Patent number
- US05914420
Reaction notes
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