1,1'-Carbonyldiimidazole → HCID 21250099, compound

HRID 1416933Notes

Reaction equation

HRID 1416933 reaction equation
[C:1]([N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)(N1C=CN=C1)=[O:2].C([CH:16]1[C:29](=[O:30])[C:28]2[C:19](=[C:20]3[C:25](=[CH:26][CH:27]=2)[CH:24]=[CH:23][CH:22]=[N:21]3)[N:18]=[CH:17]1)(O)=O>CN(C=O)C>[N:8]1([C:1]([CH:16]2[C:29](=[O:30])[C:28]3[C:19](=[C:20]4[C:25](=[CH:26][CH:27]=3)[CH:24]=[CH:23][CH:22]=[N:21]4)[N:18]=[CH:17]2)=[O:2])[CH:12]=[CH:11][N:10]=[CH:9]1

Participants

4

Reactant 2

HCID 682631,1'-CarbonyldiimidazoleHCID 21250053HCID 21250053, compound

Product 1

HCID 21250099HCID 21250099, compoundYield 92%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
100 °C

Procedure

1,1'-Carbonyldiimidazole (30.4 g) was added to a stirred mixture of 3-carboxy-4-oxo-3,4-dihydro-1,10-phenanthroline (18 g) and DMF (400 ml). The mixture was stirred at 100° C. for 2.5 hours, and then cooled to ambient temperature. The resulting solid was filtered to give 3-(imidazol-1-ylcarbonyl)-4-oxo-3,4-dihydro-1,10-phenanthroline in 92% yield.

Workup

  1. temperaturecooled to ambient temperature
  2. filtrationThe resulting solid was filtered

Sources & evidence

ORD record
ord-3383565b648842918c6220be2ab0e315
Source dataset
uspto-grants-1999_06
Patent number
US05916898

Reaction notes

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