Acetonitrile → 3-Benzyloxy-1-(2,4-difluorophenyl)-6-fluoro-7-pyrrolidin-1-yl-1H-quinazoline-2,4-dione
Reaction equation
[CH2:1]1[CH2:2][CH2:3][NH:4][CH2:5]1.[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[O:13][n:14]1[c:15](=[O:35])[n:16](-[c:27]2[c:28]([F:34])[cH:29][c:30]([F:33])[cH:31][cH:32]2)[c:17]2[cH:18][c:19]([F:26])[c:20]([F:25])[cH:21][c:22]2[c:23]1=[O:24].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[CH3:43][C:44]#[N:45]>>[CH2:1]1[CH2:2][CH2:3][N:4]([c:19]2[cH:18][c:17]3[n:16](-[c:27]4[c:28]([F:34])[cH:29][c:30]([F:33])[cH:31][cH:32]4)[c:15](=[O:35])[n:14]([O:13][CH2:6][c:7]4[cH:8][cH:9][cH:10][cH:11][cH:12]4)[c:23](=[O:24])[c:22]3[cH:21][c:20]2[F:25])[CH2:5]1Participants
5
Sources & evidence
- ORD record
- ord-7facf29872274ac4be2774fae425283b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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