Hydrochloric Acid → 1-(4-Aminoquinazoline-7-ylmethyl)piperazine-2-one

HRID 141777Notes

Reaction equation

HRID 141777 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][C:10](=[O:26])[N:11]([CH2:14][c:15]2[cH:16][cH:17][c:18]3[c:19]([NH2:25])[n:20][cH:21][n:22][c:23]3[cH:24]2)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH3:28][CH2:29][O:30][C:31]([CH3:32])=[O:33].[ClH:27]>>[NH:8]1[CH2:9][C:10](=[O:26])[N:11]([CH2:14][c:15]2[cH:16][cH:17][c:18]3[c:19]([NH2:25])[n:20][cH:21][n:22][c:23]3[cH:24]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8857Ethyl AcetateHCID 545183994-(4-Aminoquinazoline-7-ylmethyl)-3-oxo-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 179851741-(4-Aminoquinazoline-7-ylmethyl)piperazine-2-one

Sources & evidence

ORD record
ord-f247c585262c4224b81ad191a20cb4cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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