HCID 88136266, compound → Aminoacetaldehyde dimethyl acetal

HRID 1418128Notes

Reaction equation

HRID 1418128 reaction equation
[ClH:1].[Cl-].[CH3:3][O:4][CH:5]([O:25][CH3:26])[CH2:6][NH:7][CH2:8][CH2:9][C:10]12[CH2:17][CH2:16][N+:13]([CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)([CH2:14][CH2:15]1)[CH2:12][CH2:11]2>CO>[Cl-:1].[CH2:18]([N+:13]12[CH2:16][CH2:17][C:10]([CH2:9][CH2:8][Cl:1])([CH2:15][CH2:14]1)[CH2:11][CH2:12]2)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1.[CH3:3][O:4][CH:5]([O:25][CH3:26])[CH2:6][NH2:7]

Participants

4

Reactant 1

HCID 88136266HCID 88136266, compound

Product 2

HCID 89728Aminoacetaldehyde dimethyl acetalHCID 88135642HCID 88135642, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The N-[2-(1-benzyl-1-azoniabicyclo[2.2.2]-octan-4-yl)ethyl]aminoacetaldehyde-dimethylacetal-chloride-hydrochloride [melting point: 202°-204° C. (decomp.); Rf -value: 0.62 (Reversed Phase Silica gel, methanol/5% aqueous saline solution=6:4)]1 used as amine component is obtained by reaction of 1-benzyl-4-(2-chloroethyl)-1-azoniabicyclo[2.2.2]octane-chloride with aminoacetaldehyde-dimethylacetal.

Sources & evidence

ORD record
ord-e9ac3cdaf3b94380a4d3ae073c7482e0
Source dataset
uspto-grants-1999_03
Patent number
US05880284

Reaction notes

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