反应详情

A solution prepared by dissolving 19.3 g of 1-formyl-6-cyano-2-naphthol and 42.1 g of ethoxycarbonylmethyltriphenylphosphonium bromide in 140 ml of DMF was added dropwise to a solution comprising 13.6 g of anhydrous potassium carbonate and 250 ml of anhydrous methanol, followed by stirring for 3 hours under cooling with ice in a nitrogen stream and 24 hours at room temperature. The precipitate was filtered, and 2.7 liters of water was added to the filtrate, followed by stirring for 2 hours. Then, the precipitate was collected by filtration and washed with 90 ml of methanol to obtain 12.6 g of the desired product.

1. customA solution prepared
2. additionwas added dropwise to a solution
3. filtrationThe precipitate was filtered
4. addition2.7 liters of water was added to the filtrate
5. stirringby stirring for 2 hours
6. filtrationThen, the precipitate was collected by filtration
7. washwashed with 90 ml of methanol