Propylamine → HCID 178456996, compound

HRID 1419755Notes

Reaction equation

HRID 1419755 reaction equation
Cl[C:2]1[NH:7][C:6]2[CH:8]=[C:9]([Cl:11])[S:10][C:5]=2[S:4](=[O:13])(=[O:12])[N:3]=1.[CH2:14]([NH2:17])[CH2:15][CH3:16]>C(OCC)(=O)C>[Cl:11][C:9]1[S:10][C:5]2[S:4](=[O:13])(=[O:12])[N:3]=[C:2]([NH:17][CH2:14][CH2:15][CH3:16])[NH:7][C:6]=2[CH:8]=1

Participants

4

Reactant 2

HCID 7852PropylamineHCID 118320583,6-Dichloro-4h-thieno[3,2-e][1,2,4]thiadiazine 1,1-dioxide

Product 1

HCID 178456996HCID 178456996, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Conditions

Temperature
60 °C

Procedure

The title compound was prepared from 3,6-dichloro-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide and n-propylamine by a procedure analogous to the procedure described in example 1Bb, except that the mixture was stirred for 16 h at 60° C.; mp 258°-261° C. (ethyl acetate); 1H-NMR (DMSO-d6): δ 0.89 (t, 3H), 1.52 (sext, 2H), 3.15 (q, 2H), 7.05 (s, 1H), 7.29 (br. s, 1H), 10.95 (br. s, 1H).

Sources & evidence

ORD record
ord-076e04a07bd944a085f5c9c928cd0c05
Source dataset
uspto-grants-1999_03
Patent number
US05889002

Reaction notes

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