反应详情

Tin chloride dihydrate (57.9 g, 0.26 mole) in ethyl alcohol (90 ml) was added to a mixture of 2-(2-methylthioethoxy)nitrobenzene (18.1g, 0.085 mole), conc. HCl (72.4 ml) and ethyl alcohol (36 ml). The reaction mixture was stirred for 24 h at room temperature. Sodium hydroxide (6M, 270 ml) was added to the reaction mixture. Extraction with methylene chloride (3×400 ml) gave after drying the organic layer over sodium sulfate and evaporation of the solvent 14.8 g (95%) of the title compound.

1. extractionExtraction with methylene chloride (3×400 ml)
2. customgave
3. customafter drying the organic layer
4. customover sodium sulfate and evaporation of the solvent 14.8 g (95%) of the title compound