Ethylene Glycol → Ethyl 1,4-dioxaspiro(4.5)decane-8-carboxylate

HRID 142006Notes

Reaction equation

HRID 142006 reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][C:9](=[O:12])[CH2:10][CH2:11]1.[CH3:38][CH2:39][N:40]([CH2:41][CH3:42])[CH2:43][CH3:44].[CH:13]([O:14][CH3:15])([O:16][CH3:17])[O:18][CH3:19].[Cl:35][CH2:36][Cl:37].[OH:20][CH2:21][CH2:22][OH:23].[c:24]1([CH3:25])[cH:26][cH:27][c:28]([S:29]([OH:30])(=[O:31])=[O:32])[cH:33][cH:34]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]1[CH2:7][CH2:8][C:9]2([CH2:10][CH2:11]1)[O:12][CH2:22][CH2:21][O:20]2

Participants

7

Reactant 6

HCID 174Ethylene GlycolHCID 6101p-Toluenesulfonic acidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 9005Trimethyl orthoformateHCID 317638Ethyl 4-oxocyclohexanecarboxylate

Product 1

HCID 10488810Ethyl 1,4-dioxaspiro(4.5)decane-8-carboxylate

Sources & evidence

ORD record
ord-45356ae6aa504ec59d58dd1539fbf46d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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