m-Chloroperbenzoic acid → HCID 18781970, compound

HRID 1420530Notes

Reaction equation

HRID 1420530 reaction equation
[CH3:1][S:2][CH:3]1[N:6]([CH2:7][C:8](=[O:22])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14]CC2C=CC=CC=2)[C:5](=[O:23])[CH2:4]1.C1C=C(Cl)C=C(C(OO)=[O:32])C=1>>[CH3:1][S:2]([CH:3]1[N:6]([CH2:7][C:8]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)=[O:22])[C:5](=[O:23])[CH2:4]1)=[O:32]

Participants

3

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 18781937HCID 18781937, compound

Product 1

HCID 18781970HCID 18781970, compoundYield 80%

Procedure

Substituting 4-methylthio-1-phenacyl-azetidin-2-one (0.53 g, 2.25 mmol) for 4-methylthio-1-(9-phenyl-2-oxononyl)azetidin-2-one and using corresponding molar quantities of mCPBA as for Examples 5 and 6 gave 4-methylsulphinyl-1-phenacylazetidin-2-one (Example 8) as a waxy white solid (0.45 g, 80%).

Sources & evidence

ORD record
ord-802f8be5e1f440fcbd7713d260cec0e0
Source dataset
uspto-grants-2000_06
Patent number
US06071899

Reaction notes

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