1,6-Hexanediol → HCID 20663734, compound

HRID 1421349Notes

Reaction equation

HRID 1421349 reaction equation
C[C:2]1([CH3:10])[O:9][C:7](=[O:8])[CH2:6][C:4](=[O:5])[O:3]1.[OH2:11].[C:12]1([CH3:22])[CH:17]=[CH:16][C:15](S(O)(=O)=O)=[CH:14]C=1.C(O)C[CH2:25][CH2:26][CH2:27][CH2:28][OH:29]>>[C:4]([O:3][CH2:22][CH2:12][CH2:17][CH2:16][CH2:15][CH2:14][OH:11])(=[O:5])[CH2:6][C:7]([O:9][CH2:2][CH2:10][CH2:25][CH2:26][CH2:27][CH2:28][OH:29])=[O:8]

Participants

4

Reactant 3

HCID 123741,6-Hexanediol2×HCID 162492,2-Dimethyl-1,3-dioxane-4,6-dioneHCID 521998p-Toluenesulfonic acid monohydrate

Product 1

HCID 20663734HCID 20663734, compound

Procedure

A solution of bis-(6-hydroxyhexyl) malonate in 1,6-hexanediol is prepared on heating a mixture of 21.6 g (0.15 mol) of Meldrum's acid, 59 g (0.50 mol) of 1,6-hexanediol and 0.28 g (1.5 mmol) of p-toluene-sulphonic acid monohydrate for 2 hours at 140° C.

Workup

  1. temperatureon heating

Sources & evidence

ORD record
ord-35d7af5e91f24c1cb79f9def848e168e
Source dataset
uspto-grants-2000_06
Patent number
US06075106

Reaction notes

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