1-(1-Chloroethyl)-3-methoxybenzene → HCID 164678862, compound

HRID 1422373Notes

Reaction equation

HRID 1422373 reaction equation
COc1cccc(C(C)Cl)c1.ClCC/C=C/Br>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1cccc([C@@H](C)/C=C/CCCl)c1

Participants

7

Reactant 2

HCID 128614131-(1-Chloroethyl)-3-methoxybenzeneHCID 164672501HCID 164672501, compound

Product 1

HCID 164678862HCID 164678862, compoundYield 71%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-7b0b23336ede44c787ba874780ee3be9
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

Loading…