HCID 11446920, compound → HCID 162402403, compound

HRID 1422374Notes

Reaction equation

HRID 1422374 reaction equation
COc1cccc(C(C)Cl)c1.Cc1ccc(/C=C/Br)cc1>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1cccc([C@@H](C)/C=C/c2ccc(C)cc2)c1

Participants

7

Reactant 2

HCID 11446920HCID 11446920, compoundHCID 128614131-(1-Chloroethyl)-3-methoxybenzene

Product 1

HCID 162402403HCID 162402403, compoundYield 82%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-fb838f91ab174120bb816d633fa2e6c2
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

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