1-(1-Chloroethyl)-3-methoxybenzene → HCID 178490227, compound

HRID 1422375Notes

Reaction equation

HRID 1422375 reaction equation
CC(C)=CCC[C@H](C)/C=C/Br.COc1cccc(C(C)Cl)c1>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1cccc([C@@H](C)/C=C/[C@@H](C)CCC=C(C)C)c1

Participants

7

Reactant 2

HCID 128614131-(1-Chloroethyl)-3-methoxybenzeneHCID 178443921HCID 178443921, compound

Product 1

HCID 178490227HCID 178490227, compoundYield 72%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-06d7074677314586abb127c757c6eb3d
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

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