1-(1-Chloroethyl)-3-methoxybenzene → HCID 178490227, compound

HRID 1422376Notes

Reaction equation

HRID 1422376 reaction equation
CC(C)=CCC[C@H](C)/C=C/Br.COc1cccc(C(C)Cl)c1>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21.c1ccc2c(c1)C[C@H]1OC(C3(C4=N[C@H]5c6ccccc6C[C@H]5O4)CC3)=N[C@@H]21>COc1cccc([C@@H](C)/C=C/[C@@H](C)CCC=C(C)C)c1

Participants

8

Reactant 2

HCID 128614131-(1-Chloroethyl)-3-methoxybenzeneHCID 178443921HCID 178443921, compound

Product 1

HCID 178490227HCID 178490227, compoundYield 64%

Reagents, catalysts & solvents 5

HCID 5238Sodium IodideReagentHCID 9850233(3aS,3a'S,8aR,8a'R)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-06a027dd80014e70abbb3f824f7c5e16
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

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