(E)-1-(2-Bromovinyl)-4-methoxybenzene → HCID 162401029, compound

HRID 1422386Notes

Reaction equation

HRID 1422386 reaction equation
COc1ccc(/C=C/Br)cc1.Cl[C@H](Cc1ccccc1)c1ccccc1>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1ccc(/C=C/[C@H](Cc2ccccc2)c2ccccc2)cc1

Participants

7

Reactant 2

HCID 5355683(E)-1-(2-Bromovinyl)-4-methoxybenzeneHCID 92171124HCID 92171124, compound

Product 1

HCID 162401029HCID 162401029, compoundYield 80%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-f6b32bf8799e4e04a818357730f2c6e4
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

Loading…