(E)-1-(2-Bromovinyl)-4-methoxybenzene → HCID 178490130, compound

HRID 1422390Notes

Reaction equation

HRID 1422390 reaction equation
COc1ccc(/C=C/Br)cc1.C[C@@H](Cl)c1ccc2c(c1)OCO2>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1ccc(/C=C/[C@H](C)c2ccc3c(c2)OCO3)cc1

Participants

7

Reactant 2

HCID 5355683(E)-1-(2-Bromovinyl)-4-methoxybenzeneHCID 33788761HCID 33788761, compound

Product 1

HCID 178490130HCID 178490130, compoundYield 68%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-9073b8b740b64c76bd6d936e46d84fe4
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

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