(E)-1-(2-Bromovinyl)-4-methoxybenzene → HCID 178490131, compound

HRID 1422391Notes

Reaction equation

HRID 1422391 reaction equation
COc1ccc(/C=C/Br)cc1.COc1ccccc1[C@@H](C)Cl>CC(=O)N(C)C.COCCOC.[Cl][Ni][Cl].[I-].[Na+].c1ccc2c(c1)C[C@@H]1OC(C3(C4=N[C@@H]5c6ccccc6C[C@@H]5O4)CC3)=N[C@H]21>COc1ccc(/C=C/[C@H](C)c2ccccc2OC)cc1

Participants

7

Reactant 2

HCID 5355683(E)-1-(2-Bromovinyl)-4-methoxybenzeneHCID 28898614HCID 28898614, compound

Product 1

HCID 178490131HCID 178490131, compoundYield 73%

Reagents, catalysts & solvents 4

HCID 5238Sodium IodideReagentHCID 11245230(3aR,3a'R,8aS,8a'S)-2,2'-(Cyclopropane-1,1-diyl)bis(8,8a-dihydro-3aH-indeno[1,2-d]oxazole)CatalystHCID 15773433Dichloronickel;1,2-dimethoxyethaneCatalystHCID 31374DimethylacetamideSolvent

Conditions

Temperature
0 °C

Workup

  1. additionNo procedure recorded
  2. additionNo procedure recorded
  3. extractionKeep organic
  4. additionNo procedure recorded
  5. extractionKeep organic
  6. additionNo procedure recorded
  7. extractionKeep organic
  8. washNo procedure recorded
  9. dry with materialNo procedure recorded
  10. filtrationKeep filtrate
  11. concentrationNo procedure recorded

Sources & evidence

ORD record
ord-8bfa0e57bc21432e90048d6913f56a3f
Source dataset
Electroreductive Coupling of Alkenyl and Benzyl Halides
Original link
View source

Reaction notes

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