Dimethylformamide → (2-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-ethyl)-carbamic Acid Tert-butyl Ester

HRID 142475Notes

Reaction equation

HRID 142475 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][I:10])=[O:11].[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][c:21]1[c:22]([N:28]2[CH2:29][C:30](=[O:41])[N:31]([CH2:35][CH2:36][Si:37]([CH3:38])([CH3:39])[CH3:40])[S:32]2(=[O:33])=[O:34])[cH:23][cH:24][c:25]([I:27])[cH:26]1.[CH3:47][CH2:48][O:49][C:50]([CH3:51])=[O:52].[I-:12].[O:42]=[CH:43][N:44]([CH3:45])[CH3:46].[Zn:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH2:8][CH2:9][c:25]1[cH:24][cH:23][c:22]([N:28]2[CH2:29][C:30](=[O:41])[N:31]([CH2:35][CH2:36][Si:37]([CH3:38])([CH3:39])[CH3:40])[S:32]2(=[O:33])=[O:34])[c:21]([O:20][CH2:13][c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:26]1)=[O:11]

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 23994ZincHCID 30165Iodide IonHCID 641024tert-butyl N-(2-iodoethyl)carbamateHCID 667569375-(2-Benzyloxy-4-iodophenyl)-1,1-dioxo-2-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-3-one

Product 1

HCID 68842331(2-{3-Benzyloxy-4-[1,1,4-trioxo-5-(2-trimethylsilanylethyl)-1,2,5-thiadiazolidin-2-yl]-phenyl}-ethyl)-carbamic Acid Tert-butyl Ester

Sources & evidence

ORD record
ord-8a319eeb6708478e8f8f3271a7028192
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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