反应详情

A solution of 5-(5-methoxy-pyridin-2-ylmethoxy)-2-(tetrahydro-pyran-2-yl)-2H-pyridazin-3-one (500 mg, 1.58 mmol) in a mixture of MeOH (5 mL) and concentrated aqueous HCl (0.65 mL) is heated at reflux for 2 h. Most of the volatiles are removed under reduced pressure and water is added. The formed precipitate is filtered off and dried.

1. temperatureis heated
2. temperatureat reflux for 2 h
3. customMost of the volatiles are removed under reduced pressure and water
4. additionis added
5. filtrationThe formed precipitate is filtered off
6. customdried