Nitromethane → HCID 72709585, compound

HRID 1427686Notes

Reaction equation

HRID 1427686 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]2[C:10](=[CH:11][CH:12]=1)[NH:9][C:8](=[O:13])[C:7]2=[O:14])([O-:3])=[O:2].[N+:15]([CH3:18])([O-:17])=[O:16]>O>[OH:14][C:7]1([CH2:18][N+:15]([O-:17])=[O:16])[C:6]2[C:10](=[CH:11][CH:12]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[NH:9][C:8]1=[O:13]

Participants

4

Reactant 2

HCID 6375NitromethaneHCID 46692505-Nitroisatin

Product 1

HCID 72709585HCID 72709585, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
30 °C

Procedure

5-nitroisatin (0.081 g) and nitromethane (0.15 ml) were added to water (2 ml) and the reaction mixture was vigorously stirred at a temperature of 30° C. for 12 hours. The product was extracted with ethyl acetate and recrystallized with MeOH to afford pure product.

Workup

  1. extractionThe product was extracted with ethyl acetate
  2. customrecrystallized with MeOH
  3. customto afford pure product

Sources & evidence

ORD record
ord-5dd39c0333bc45c9b481db8caf50b5d0
Source dataset
uspto-grants-2015_01
Patent number
US08933248B2

Reaction notes

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