Nitromethane → HCID 72709670, compound

HRID 1427694Notes

Reaction equation

HRID 1427694 reaction equation
[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7](=[O:14])[C:6]1=[O:15].[N+:20]([CH3:23])([O-:22])=[O:21]>O>[Cl:1][C:2]1[CH:19]=[CH:18][CH:17]=[CH:16][C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]([OH:14])([CH2:23][N+:20]([O-:22])=[O:21])[C:6]1=[O:15]

Participants

4

Reactant 2

HCID 6375NitromethaneHCID 15810621-(2-chlorobenzyl)-1H-indole-2,3-dione

Product 1

HCID 72709670HCID 72709670, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
30 °C

Procedure

1-(2-chlorobenzyl)indoline-2,3-dione (0.135 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 9 hours. The obtained product was extracted with ethyl acetate and the solvent was removed to give pure product.

Workup

  1. extractionThe obtained product was extracted with ethyl acetate
  2. customthe solvent was removed
  3. customto give pure product

Sources & evidence

ORD record
ord-5d371e4186424d6da5c917de993e8f83
Source dataset
uspto-grants-2015_01
Patent number
US08933248B2

Reaction notes

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