Nitromethane → HCID 72709672, compound

HRID 1427697Notes

Reaction equation

HRID 1427697 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[CH2:4][N:5]1[C:13]2[C:8](=[CH:9][C:10]([Cl:14])=[CH:11][CH:12]=2)[C:7](=[O:15])[C:6]1=[O:16].[N+:21]([CH3:24])([O-:23])=[O:22]>O>[Cl:14][C:10]1[CH:9]=[C:8]2[C:13](=[CH:12][CH:11]=1)[N:5]([CH2:4][C:3]1[CH:17]=[CH:18][CH:19]=[CH:20][C:2]=1[Cl:1])[C:6](=[O:16])[C:7]2([OH:15])[CH2:24][N+:21]([O-:23])=[O:22]

Participants

4

Reactant 2

HCID 6375NitromethaneHCID 2196453HCID 2196453, compound

Product 1

HCID 72709672HCID 72709672, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
30 °C

Procedure

1-(2-chlorobenzyl)-5-chloroindoline-2,3-dione (0.153 g) and nitromethane (0.15 ml) were added to water and the reaction mixture was vigorously stirred at a temperature of 30° C. for 18 hours. The formed solid product was filtered and recrystallized with MeOH to afford pure product.

Workup

  1. filtrationThe formed solid product was filtered
  2. customrecrystallized with MeOH
  3. customto afford pure product

Sources & evidence

ORD record
ord-cffa9cbb4f11452a81c75b8f9f2fb6d6
Source dataset
uspto-grants-2015_01
Patent number
US08933248B2

Reaction notes

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