Tetrahydrofuran → tert-butyl (5-{5-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]pyrazin-2-yl}-2H-tetrazol-2-yl)acetate
Reaction equation
[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][cH:13][c:14](-[c:17]4[n:18][n:19][nH:20][n:21]4)[n:15][cH:16]3)[CH2:9][CH2:10]2)[cH:22][c:23]([F:26])[cH:24][cH:25]1.[Br:34][CH2:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:27][CH2:28][N:29]([CH2:30][CH3:31])[CH2:32][CH3:33]>>[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([c:11]3[n:12][cH:13][c:14](-[c:17]4[n:18][n:19][n:20]([CH2:35][C:36](=[O:37])[O:38][C:39]([CH3:40])([CH3:41])[CH3:42])[n:21]4)[n:15][cH:16]3)[CH2:9][CH2:10]2)[cH:22][c:23]([F:26])[cH:24][cH:25]1Participants
5
Sources & evidence
- ORD record
- ord-45710c42a5ac4d71b59bd120da04d61a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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