P-Xylene → 1-(2,5-Dimethylphenyl)-2-methyl-2-propen-1-one

HRID 1428439Notes

Reaction equation

HRID 1428439 reaction equation
[C:1]1([CH3:8])[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][CH:2]=1.[C:9](Cl)(=[O:13])[C:10]([CH3:12])=[CH2:11].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[CH3:8][C:1]1[CH:6]=[CH:5][C:4]([CH3:7])=[CH:3][C:2]=1[C:9](=[O:13])[C:10]([CH3:12])=[CH2:11]

Participants

5

Reactant 3

HCID 7809P-XyleneHCID 13528Methacryloyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 5944291-(2,5-Dimethylphenyl)-2-methyl-2-propen-1-one

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Paraxylene (1 mL), methacryloyl chloride (110 mg), and aluminium chloride (160 mg) were reacted in dichloromethane (1.5 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (140 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-202e3ba202ea4b33a995eccc9c430198
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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