Anisole → HCID 46913386, compound

HRID 1428450Notes

Reaction equation

HRID 1428450 reaction equation
[C:1]1([O:7][CH3:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:9](Cl)(=[O:14])/[C:10](=[CH:12]/[CH3:13])/[CH3:11].[Cl-].[Al+3].[Cl-].[Cl-]>ClCCl>[CH3:8][O:7][C:1]1[CH:6]=[CH:5][C:4]([C:9](=[O:14])/[C:10](=[CH:12]/[CH3:13])/[CH3:11])=[CH:3][CH:2]=1

Participants

5

Reactant 3

HCID 7519AnisoleHCID 5325503(2E)-2-Methyl-2-butenoyl chlorideHCID 6451240Aluminum(III) Chloride

Product 1

HCID 46913386HCID 46913386, compoundYield 28%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Anisole (128 mg), tigloyl chloride (140 mg), and aluminium chloride (155 mg) were reacted in dichloromethane (1.5 mL) at from 0° C. to room temperature for 4 hours. The resultant was treated in the same manner as described in Example 1 to obtain the title compound (63 mg).

Workup

  1. additionThe resultant was treated in the same manner

Sources & evidence

ORD record
ord-ffa371fd5edf4817b2e522c2d8abfa6a
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

Loading…