Benzaldehyde → alpha-Vinylbenzyl alcohol

HRID 1428465Notes

Reaction equation

HRID 1428465 reaction equation
[CH:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9]([Mg]Br)=[CH2:10]>C1COCC1>[CH:9]([CH:1]([C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1)[OH:8])=[CH2:10]

Participants

4

Reactant 2

HCID 240BenzaldehydeHCID 178418507HCID 178418507, compound

Product 1

HCID 92986alpha-Vinylbenzyl alcohol

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Benzaldehyde (342 mg) was mixed with THF (4 ml) and further mixed with vinylmagnesium bromide (1 N solution) (4 mL), followed by stirring for 12 hours to obtain the title compound (320 mg).

Sources & evidence

ORD record
ord-4cf16dc070d24510817501328d62ee98
Source dataset
uspto-grants-2015_01
Patent number
US08937091B2

Reaction notes

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