Bromide ion → 1-(2-Chloro-9,10-dihydro-9,10-methanoanthracen-9-ylmethyl)-4-(1,1-dimethylethyl)piperidin-4-ol

HRID 142902Notes

Reaction equation

HRID 142902 reaction equation
[Br-:2].[C:3]([CH3:4])([CH3:5])([CH3:6])[Li:7].[Cl:8][c:9]1[cH:10][c:11]2[c:20]([cH:21][cH:22]1)[CH:19]1[c:18]3[c:13]([cH:14][cH:15][cH:16][cH:17]3)[C:12]2([CH2:24][N:25]2[CH2:26][CH2:27][C:28](=[O:31])[CH2:29][CH2:30]2)[CH2:23]1.[Li+:1].[O:32]1[CH2:33][CH2:34][CH2:35][CH2:36]1>>[C:3]([CH3:4])([CH3:5])([CH3:6])[C:28]1([OH:31])[CH2:27][CH2:26][N:25]([CH2:24][C:12]23[c:11]4[cH:10][c:9]([Cl:8])[cH:22][cH:21][c:20]4[CH:19]([c:18]4[c:13]2[cH:14][cH:15][cH:16][cH:17]4)[CH2:23]3)[CH2:30][CH2:29]1

Participants

6

Reactant 5

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 214806221-(2-Chloro-9,10-dihydro-9,10-methanoanthracen-9-ylmethyl)-4-piperidinoneHCID 178418306HCID 178418306, compound

Product 1

HCID 214806871-(2-Chloro-9,10-dihydro-9,10-methanoanthracen-9-ylmethyl)-4-(1,1-dimethylethyl)piperidin-4-ol

Sources & evidence

ORD record
ord-6cd3e06a2896425c8934d73e07425336
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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