Magnesium ethanolate → HCID 178525631, compound

HRID 1429308Notes

Reaction equation

HRID 1429308 reaction equation
[C:1]([O:7][CH2:8][CH3:9])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[O-]CC.[Mg+2:13].[O-]CC>C1COCC1>[C:1]([O-:7])(=[O:6])[CH2:2][C:3]([O-:5])=[O:4].[CH2:8]([Mg+2:13])[CH3:9]

Participants

4

Reactant 2

HCID 164963Magnesium ethanolateHCID 3595298Propanedioic acid, monoethyl ester

Product 1

HCID 178525631HCID 178525631, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

To a stirred solution of monoethyl malonate 1(1.65 g, 12.5 mmol) in THF (25 mL) was added the magnesium ethoxide (0.61 g, 6.25 mmol). The reaction mixture was allowed to stir at rt for 5 h (until the solution become clear). The result solution was used for next step without any treatment.

Sources & evidence

ORD record
ord-6bf30d76f105458abf336a2d91aa06a1
Source dataset
uspto-grants-2015_01
Patent number
US08940506B2

Reaction notes

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