Dimethylformamide → HCID 86611311, compound

HRID 1431973Notes

Reaction equation

HRID 1431973 reaction equation
Br[C:2]1[CH:3]=[C:4]([C:17]2[CH:22]=[CH:21][C:20]3[O:23][CH2:24][O:25][C:19]=3[CH:18]=2)[N:5]([S:7]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([Cl:16])[CH:11]=2)(=[O:9])=[O:8])[CH:6]=1.C([Li])(C)(C)C.CN([CH:34]=[O:35])C>>[Cl:16][C:12]1[CH:11]=[C:10]([S:7]([N:5]2[CH:6]=[C:2]([CH:34]=[O:35])[CH:3]=[C:4]2[C:17]2[CH:22]=[CH:21][C:20]3[O:23][CH2:24][O:25][C:19]=3[CH:18]=2)(=[O:9])=[O:8])[CH:15]=[CH:14][CH:13]=1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 68615631HCID 68615631, compoundHCID 178418306HCID 178418306, compound

Product 1

HCID 86611311HCID 86611311, compound

Procedure

The title compound is prepared from 4-bromo-1-(m-chlorobenzensulfonyl)-2-(3,4-methylenedioxyphenyl)-pyrrole, tert-butyl lithium and DMF following the procedure of Example 3a. 1H-NMR (300 MHz, CDCl3): 9.89 (s, 1H); 8.08 (d, J=2.0 Hz, 1H); 7.6-7.5 (m, 1H); 7.4-7.25 (m, 4H); 6.8-6.7 (m, 1H); 6.65-6.55 (m, 1H); 6.55 (d, J=2.0, 1H); 6.05 (s, 2H).

Sources & evidence

ORD record
ord-40e1f76dd25242579377ab9c18a04120
Source dataset
uspto-grants-2009_11
Patent number
US07612064B2

Reaction notes

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