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HRID1432336

反应详情

EQUATION

反应方程式

HRID 1432336 的结构方程式

REACTANTS

反应物

2
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：CCCCNC(=O)[C@H](C)C[C@H](O)[C@H](Cc1cccc(OCc2ccccc2)c1)NC(=O)OC(C)(C)C
HCID11648991

未命名化合物

PRODUCTS

生成物

1
结构：CCCCNC(=O)[C@H](C)C[C@H](O)[C@@H]([NH3+])Cc1cccc(OCc2ccccc2)c1.[Cl-]
HCID86612512

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1COCCO1
溶剂HCID31275

1,4-Dioxane

C4H8O2

PROCEDURE

实验过程

[(1S*,2S*,4R*)-1-(3-Benzyloxy-benzyl)-4-butylcarbamoyl-2-hydroxy-pentyl]-carbamic acid tert-butyl ester (660 mg, 1.3 mmol) is dissolved in 4M HCl in dioxane (14 ml) and stirred at rt for 75 min. Evaporation of the solvent and washing the residue with diethyl ether gives a white foam (535 mg).

WORKUP

后处理

  1. customEvaporation of the solvent
  2. washwashing the residue with diethyl ether