反应详情

To a solution of 2-(1H-indol-3-yl)-ethylamine (1.0 g) in CH2Cl2 was added at 22° C. NEt3 (1.74 ml) and 3,5-bis-trifluoromethyl-benzoyl chloride (1.24 ml) and stirring was continued at 22° C. for 16 h. The mixture was washed with aqueous NaHCO3 and brine and the organic layer was dried and evaporated to give the title compound as a brown solid. MS: 401.3 ([M+H]+).

1. washThe mixture was washed with aqueous NaHCO3 and brine
2. customthe organic layer was dried
3. customevaporated