HRID1432475

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID240

Benzaldehyde

C7H6O

HCID10751398

未命名化合物

HCID69069334

未命名化合物

PRODUCTS

生成物

结构：CC(=O)NCCc1c(C(C2=C(O)C(CCC3CCCCC3)OC2=O)c2ccccc2)[nH]c2cc(F)ccc12

HCID57933469

未命名化合物

PROCEDURE

实验过程

Using general procedure C, 5-(2-cyclohexyl-ethyl)-4-hydroxy-5H-furan-2-one (Example B2) was reacted with benzaldehyde and N-[2-(6-fluoro-1H-indol-3-yl)-ethyl]-acetamide (Example 18.1.) to give the title compound as pale green solid. MS: 517.2 ([M−H]−).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8a2c29cc2d344b00a413c6d4141afabf
来源数据集: uspto-grants-2009_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07612099B2
来源说明: uspto-grants-2009_11

反应 SMILES

[CH:1]1([CH2:7][CH2:8][CH:9]2[O:13][C:12](=[O:14])[CH:11]=[C:10]2[OH:15])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH:16](=O)[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1.[F:24][C:25]1[CH:33]=[C:32]2[C:28]([C:29]([CH2:34][CH2:35][NH:36][C:37](=[O:39])[CH3:38])=[CH:30][NH:31]2)=[CH:27][CH:26]=1>>[CH:1]1([CH2:7][CH2:8][CH:9]2[O:13][C:12](=[O:14])[C:11]([CH:16]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:30]3[NH:31][C:32]4[C:28]([C:29]=3[CH2:34][CH2:35][NH:36][C:37](=[O:39])[CH3:38])=[CH:27][CH:26]=[C:25]([F:24])[CH:33]=4)=[C:10]2[OH:15])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1